Design of Experiments: A Primer

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Design of experiments (DOE) is a systematic method to determine the relationship between factors affecting a process and the output of that process. In other words, it is used to find cause-and-effect relationships. This information is needed to manage process inputs in order to optimize the output. An understanding of DOE first requires […]

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Case Study: Using DFSS and DOE to Increase Product Reliability

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A medical devices company, developing technology to enable smaller medical devices, launched a substrate development effort as part of a larger-scale technology and product development effort. The substrate development effort involved predicting the stress caused by the laser welding process to ensure product reliability. In this Design for Six Sigma (DFSS) case study, design and […]

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Reducing Variability with DOE – A Case Study on Propagation of Error (POE)

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The Therabath paraffin therapy bath (pictured below) is a durable medical device that holds one gallon of molten paraffin wax. Sufferers of osteoarthritis use it for physical therapy. They dip their hands repeatedly in the heated bath, which helps loosen stiff joints. The wax then slowly solidifies as a glove, producing further therapeutic benefits via […]

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Case Study: Using DOE to Reduce Wasted Supplies in CTU

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The quality of environmental hygiene in hospitals is under increasing scrutiny from both healthcare providers and consumers because the prevalence of serious infections due to multidrug-resistant pathogens has reached alarming levels. The transfer of gram-positive bacteria, particularly methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE), among patients is a growing concern. One critical factor for […]

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Six Sigma Can Drive Environmental Management Programs

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The current ISO 14001:2004 standard for environmental management systems has explicit requirements for defining and establishing objective targets and measures as part of an organizationโ€™s commitment to sound environmental management. Meeting these standards can be made easier when Six Sigma is applied in complement to an organizationโ€™s environmental management system. The presence of a robust […]

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Using DOE to Solve a Product Development Problem – An iSixSigma Case Study

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Design of experiments (DOE) is a useful tool for determining specific factors affecting defect levels in a product. A major automotive company learned just how valuable this tool is when it conducted a study of defects occurring in its alternator product. DOE was applied to identify the cause of ventilation noise within the alternator, a […]

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